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KMID : 0358920070340010130
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Journal of the Korean Academy of Pedodontics
2007 Volume.34 No. 1 p.130 ~ p.139
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The dental caries, cariogenic microorganisms and levels of salivary immunoglobulin in subjects with down’s syndrome
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Kim Seon-Mi
Yang Kyu-Ho
Choi Nam-Ki
Kang Mi-Sun
Lim Hoi-Soon
Oh Jong-Suk
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Abstract
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This study investigated the relationship between dental caries and various oral factors in subjects with Down’ s syndrome. We compared 25 subjects with Down’s syndrome with 63 healthy control. The dental caries index and plaque index were examined, and the total salivary immunoglobulin A and S. mutans specific salivary immunoglobulin A concentration were measured using ELISA. The S. mutans counts, Lactobacillus counts and buffer capacity were measured with Dentocult test medium.
The decayed and filled surface index of deciduous teeth in subjects with Down’ s syndrome was lower than in controls(p<0.001). The plaque index and total salivary immunoglobulin A concentration showed no difference, S. mutans specific salivary immunoglobulin A concentration and buffer capacity in subjects with Down’ s syndrome were lower than in controls(p<0.001). There was no significant difference between two groups in the S. mutans counts and Lactobacillus counts. In 9-11 year age group, S. mutans counts in subjects with Down’ s syndrome was lower than in controls(p(0.001) and S. mutans specific salivary immunoglobulin A concentration was lower(p(0.05). There was a high correlation among deciduous dental caries index and buffering capacity and S. mutans counts.
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KEYWORD
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down’s syndrome, dental caries, sterptococcus mutans, buffer capacity, salivary immunoglobulin A, streptococcus mutans-specific salivary immunoglobulin A
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